Hilary Godwin

Type of Faculty: 
fulltime
Appointment Title: 
Professor
Address: 
UCLA Fielding School of Public Health 650 Charles E. Young Drive South 66-062B CHS Los Angeles, CA 90095
310.794.9112 (office)/ 310.794.5496 (lab)
310.794.2106
Biographical Information: 

Professor Godwin joined the UCLA faculty in 2006 and is currently a Professor in the Environmental Health Sciences Department and in the Institute of the Environment and Sustainability. She received a B.S. in Chemistry from the University of Chicago in 1989 and a Ph.D. Physical Chemistry from Stanford University in 1994. She conducted postdoctoral research from 1994-1996 at the Johns Hopkins University School of Medicine in the Department of Biophysics and Biophysical Chemistry, where she was a National Institutes of Health postdoctoral fellow. Prior joining the faculty at UCLA, Dr. Godwin was on the faculty of the Department of Chemistry at Northwestern University, where she was an Assistant Professor (1996-2000), Associate Professor (2000-2006), Associate Chair (2003-2004), and Chair (2004-2006) of Chemistry.  She has served as Chair of the Department of Environmental Health Sciences (2007-2008) Associate Dean for Academic Programs (2008-2011) in the School of Public Health at UCLA as well as Faculty Director for the Global Bio Lab at UCLA (2009-2011).  Dr. Godwin has received several awards, including a Camille Dreyfus Teacher-Scholar Award, an Alfred P. Sloan Research Fellowship, a National Science Foundation CAREER Award, a Burroughs Wellcome Fund Toxicology New Investigator Award, and a Camille and Henry Dreyfus New Faculty Award. She was a Howard Hughes Medical Institute Professor from 2002-2006 and was elected as a fellow of the AAAS in 2009.  Dr. Godwin is a Luskin Scholar and is coPI and Director for Education and Outreach Activities for the University of California Center for Environmental Implications of Nanotechnology.  Dr. Godwin's research focuses on elucidating the molecular toxicology of engineered nanomaterials and development of assays for detection and analysis of infectious diseases. She collaborates with Professor Tim Malloy in the UCLA School of Law on the development and analysis of new approaches to nanoregulatory policy and assessment of alternatives for hazardous substances.  She also works actively with local organizations and community groups to prepare for and diminish the impact of climate change on public health.

Education: 
PhD, Physical Chemistry, Stanford University
BS, Chemistry, with honors, University of Chicago
Areas of Interest: 
Infectious diseases
Selected Publications: 

“Zebrafish High-Thoughput Screening to Study the Impact of Dissolvable Metal Oxide Nanoparticles on the Hatching Enzyme, ZHE1” Lin, s.; Zhao, Y.; Ji, Z.; Ear, J.; Chang, C. H.; Zhang, H.; Low-Kam, C.; Yamada, K.; Meng, H.; Wang, X.; Liu, R.; Pokhrel, S; Mädler, L.; Damoiseaux, R.; Xia, T.; Godwin, H. A.; Lin, S.;   Nel, A. E. Small  2013, in press; article first published online : 23 NOV 2012, DOI: 10.1002/smll.201202128.

"Implementation of a Multidisciplinary Approach to Solve Complex Nano EHS problems by the UC Center for the Environmental Implications of Nanotechnology" Xia, T.; Malasarn, D.; Lin, S.; Ji, Z.; Zhang, H.; Miller, R. J.; Keller, A. A.; Nisbet, R. M.; Harthorn, B. H.; Godwin, H. A.; Lenihan, H. S.; Liu, R.; Gardea-Torresdey, J.; Cohen, Y.; Mädler, L.; Holden, P. A.; Zink, J. I.; Nel. A. E. Small  2012, in press; article first published online: 2 OCT 2012, DOI: 10.1002/smll.201201700.

“Genome-wide Bacterial Toxicity Screening Uncovers the Mechanisms of Toxicity of Cationic Polystyrene Nanomaterials” Ivask, A; Suarez, E.; Patel, T.; Boren, D.; Ji, Z.; Holden, P.; Telesca, D.; Damoiseaux, R.; Bradley, K.; Godwin, H. Environ. Sci. Technol., 2012, 46, 2398-2405.

“Dispersion and Stability Optimization of TiO2 Nanoparticles in Cell Culture Media<http://pubs.acs.org/doi/abs/10.1021/es100417s?prevSearch=%5Bauthor%3A%2BGodwin%5D&searchHistoryKey=>” Ji, Z.; Jin, X.; George, S.; Xia, T.; Meng, H.; Wang, X.; Suarez, E.; Zhang, H.; Hoek, E. M. V.; Godwin, H. Nel, A. E.; Zink, J. I. Environ. Sci. Technol., 2010, 44, 7309–7314.

“Coffee Cup Atomic Force Microscopy” Ashkenaz, D. E.; Hall, W. P.; Haynes, C. L.; Hicks, E. M.; McFarland, A. D.; Sherry, L.J.; Stuart, D. A.; Wheeler, K. E.; Yonzon, C. R.; Zhao, J.; Godwin, H.A.; Van Duyne, R. P. J. Chem. Ed., 2010, 87, 306-307.

“The University of California Center for the Environmental Implications of Nanotechnology” Godwin, H. A.; Chopra, K.; Bradley, K. A.; Cohen, Y.: Harthorn, B. H.; Hoek, E. M. V.; Holden, P.; Keller, A. A.; Lenihan, H.; Nesbit, R.; Nel, A. E. Environ. Sci. & Tech., 2009, 43, 6453–6457.

 “A recombinant courtship pheromone affects sexual receptivity in a plethodontid salamander” Houck, L.; Watts, R.; Arnold, S.; Bowen, K.; Kiemnec, K.; Godwin, H.; Feldhoff, P.; Feldhoff, R. Chem. Senses, 2008, 33, 623 - 631.

Andersen, R. J.; diTargani, R. C.; Hancock, R. D.; Stern, C. L.; Goldberg, D. P.; Godwin, H. A. Characterization of the first N2S(alkylthiolate)lead compound: A model for 3-coordinate lead in biological systems. Inorg. Chem.. 2006; 45: 16574-16576.

Mayer, R. A.; Godwin, H. A. Preparation of Media and Buffers with Soluble Lead (Pb2+). Anal. Biochem.. 2006; 356: 142-144.

McFarland, A.D.; Haynes, C.L.; Van Duyne, R.; Godwin, H.A. Nanopatterning with Lithography. J. Chem. Ed. . 2005; 82: 768A-768B

Magyar, J.S.;Weng, T.C.; Stern, C.M.; Dye, D.F.; Rous, B.W.; Payne, J.C.; Bridgewater, B.M.; Milovilovich, A.; Parkin, G.;Zaleski, J.M.; Penner-Hahn, J.E.; Godwin, H.A. Reexamination of Lead(II) Coordination Preferences in Sulfur-Rich Sites: Implications for a Critical Mechanism of Lead Poisoning. J. Am. Chem. Soc.. 2005; 127: 9495-9505.

Ghering, A.B.; Jenkins, L.M.M.; Schenck, B.L.; Deo, S.;Mayer, R.A.;Pikaart, M.J.;Omichinski, J.G.; Godwin, H.A. Spectroscopic and Functional Determination of the Interaction of Pb2+ with GATA Proteins. J Am. Chem. Soc. . 2005; 127: 3751-3759.

Godwin, H.A.; Davis, B.L. Teaching Undergraduates at the Interface of Chemistry and Biology: Challenges and the Opportunities. Nature Chem. Biol. . 2005; 1: 176-179.

McFarland, Adam D.; Haynes, Christy L.; Mirkin, Chad A.; Van Duyne, Richard P.; Godwin, Hilary A. Color My Nanoworld. J. Chem. Educ.2004. 2004; 81: 544A-544B.

Garcia, R. A. and Godwin, H. A. High Metal Concentrations Are Required for Self-Association of Synaptotagmin II. Biophys. J. 2004; 86: 2455-2466 .

Ghering, A. B.; Shokes, J. E.; Scott, R. A.; Omichinski, J. G.; Godwin, H. A. Spectroscopic Determination of the Thermodynamics of Cobalt and Zinc Binding to GATA Proteins. Biochemistry. 2004; 43: 8346-8355.

Claudio, E. S.; Magyar, J. S.; Godwin, H. A. Fundamental Coordination Chemistry, Environmental Chemistry, and Biochemistry of Lead(II). Prog. Inorg. Chem. 2003; 51: 1-144.

Magyar, J. S.; Godwin, H. A. Spectropotentiometric Analysis of Metal Binding to Structural Zinc-Binding Sites: Accounting Quantitatively for pH and Metal Ion Buffering Effects. Anal. Biochem. . 2003; 320: 39-54.

Payne, J. C;. Rous, B. W.; Tenderholt, A. L; Godwin, H. A. Spectroscopic Determination of the Binding Affinity of Zinc to the DNA-Binding Domains of Nuclear Hormone Receptors. Biochemistry. 2003; 42: 14214-14224.

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